Health Conditions
Folate Deficiency
Low folate that can cause anaemia.
Overview
Folate (vitamin B9) is needed for cell growth and division, and is especially important during pregnancy for preventing neural tube defects. Deficiency is often linked to diet, alcohol use, or conditions affecting absorption.
Symptoms
Fatigue, weakness, pale skin, irritability, shortness of breath, and mouth soreness. Symptoms overlap significantly with B12 deficiency, so both are often tested together.
Risk Factors
Poor diet low in leafy greens and fortified grains, alcohol use disorder, pregnancy, malabsorption conditions (coeliac disease, inflammatory bowel disease), and certain medications (e.g. some anti-epileptics, methotrexate).
Common Blood Tests
Serum or red blood cell folate levels, usually alongside vitamin B12 to distinguish between the two causes of megaloblastic anaemia.
Lifestyle Information
Leafy green vegetables, legumes, citrus fruit, and fortified cereals are good dietary sources. Folic acid supplementation is specifically recommended before and during early pregnancy.
When to seek medical advice
Talk to a doctor if you're pregnant or planning pregnancy and haven't discussed folic acid supplementation, or if you have symptoms of anaemia.